Prevention of ischemic-type biliary lesions by arterial back-table pressure perfusion
نویسندگان
چکیده
منابع مشابه
Ischemic Type Biliary Lesions
Liver transplantation (LT) is an established therapy for end-stage liver disease based on a substantial progress in surgical and immunological management of concomitant posttransplant phenomena. Apart from rejection and HCV-recurrence, the development of biliary strictures is one of the most serious complications observed after LT significantly affecting graft and patient survival [1, 2]. Frequ...
متن کاملLiver Preservation by Aortic Perfusion Alone Compared With Preservation by Aortic Perfusion and Additional Arterial Ex Situ Back-Table Perfusion With Histidine-Tryptophan-Ketoglutarate Solution: A Prospective, Randomized, Controlled, Multicenter Study
BACKGROUND Arterial ex situ back-table perfusion (BP) reportedly reduces ischemic-type biliary lesion after liver transplantation. We aimed to verify these findings in a prospective investigation. METHODS Our prospective, randomized, controlled, multicenter study involved livers retrieved from patients in 2 German regions, and compared the outcomes of standard aortic perfusion to those of aor...
متن کاملCauses and consequences of ischemic-type biliary lesions after liver transplantation.
Biliary complications are a major source of morbidity, graft loss, and even mortality after liver transplantation. The most troublesome are the so-called ischemic-type biliary lesions (ITBL), with an incidence varying between 5% and 15%. ITBL is a radiological diagnosis, characterized by intrahepatic strictures and dilatations on a cholangiogram, in the absence of hepatic artery thrombosis. Sev...
متن کاملIncidence of and risk factors for ischemic-type biliary lesions following orthotopic liver transplantation.
Ischemic-type biliary lesions (ITBL) account for a major part of patients' morbidity and mortality after orthotopic liver transplantation (OLT). The exact origin of this type of biliary complication remains unknown. This study retrospectively evaluated 1843 patients. Patients with primary sclerosing cholangitis were excluded from this study. The diagnosis of ITBL was established only when all o...
متن کاملEfficacy of sirolimus on ischemic-type biliary lesions after liver transplantation
Objective: To explore and summarize the effect of sirolimus on ischemic-type biliary lesions (ITBL) after liver transplantation. Methods: A retrospective study was carried out on 52 patients using sirolimus for biliary complications after liver transplantation from 2004 to 2016 in our hospital. Serum alanine transaminase (ALT), aspartate transaminase (AST), total bilirubin, glutamyl endopeptida...
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ژورنال
عنوان ژورنال: Liver Transplantation
سال: 2003
ISSN: 1527-6465
DOI: 10.1053/jlts.2003.50015